Sulphamethoxazole combined with 2-4-diamino-pyrimidines in the treatment of gonorrhoea.
نویسندگان
چکیده
منابع مشابه
Sulphamethoxazole combined with 2-4-diamino-pyrimidines in the treatment of gonorrhoea.
THE synergistic action of the combination ofsulphonamides and 2-4-diamino-pyrimidine compounds against the gonococcus has been demonstrated clinically by Csonka and Knight (1967). It was decided to reassess the clinical efficacy of the combination of trimethoprim with sulphamethoxazole* in gonorrhoea, to examine its mode of action, and to compare the effect of a combination of another pyrimidin...
متن کاملSulphamethoxazole-trimethoprim in the treatment of gonorrhoea.
SELECTION OF PATIENTS All patients who attended the Plymouth clinic during that period and from whom smears and cultures yielded gonococci were included in the trial with the following exceptions: (i) Pregnant women (ii) Known prostitutes (iii) Men with gonococcal proctitis (iv) Patients who had defaulted on previous occasions (v) Patients who would be unable to attend for regular follow-up. A ...
متن کاملTreatment of gonorrhoea with trimethoprim-sulphamethoxazole in Uganda.
Penicillin is still satisfactory as the main treatment for gonorrhoea in Uganda, but there is evidence that its usefulness is declining. In 1961, there was a treatment failure rate of only 4 per cent. with a single dose of 0-3 mega units penicillin aluminium mono-stearate (PAM) (Kibukamusoke, 1965); four times that dose-1V2 mega units-gave a failure' rate of 17-9 per cent. in 1966 (Arya, unpubl...
متن کاملTrimethoprim-sulphamethoxazole (Septrin) in the treatment of rectal gonorrhoea.
The recent increase in some parts of London of syphilis acquired homosexually (Lancet, 1964; Brit. med. J7., 1967) has indicated that a drug of nontreponemicidal properties is to be preferred in the treatment of gonococcal proctitis in homosexual men. Septrin was considered as a potentially useful remedy in these circumstances. Though taken orally and so subject to error or misuse, it needs be ...
متن کاملTrimethoprim-sulphamethoxazole in gonorrhoea. A comparison with privampicillin combined with probenecid.
419 patients with uncomplicated gonorrhoea were treated with sulphamethoxazole 4 g. combined with trimethoprim 0-8 g. divided into two doses with an 8-hr interval. The failure rate was 1-9 per cent. Parallel with this trial, 319 patients received pivampicillin 1-4 g. combined with probenecid 1 g,; the failure rate was 0-9 per cent. Side-effects were few, four patients in the first group and one...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Sexually Transmitted Infections
سال: 1970
ISSN: 1368-4973
DOI: 10.1136/sti.46.1.34